Seo, Jai Woong Baek, Hyounggee Mahakian, Lisa M Kusunose, Jiro Hamzah, Juliana Ruoslahti, Erkki Ferrara, Katherine W
Published in
Bioconjugate chemistry
The ability to detect and quantify macrophage accumulation can provide important diagnostic and prognostic information for atherosclerotic plaque. We have previously shown that LyP-1, a cyclic 9-amino acid peptide, binds to p32 proteins on activated macrophages, facilitating the visualization of atherosclerotic plaque with PET. Yet, the in vivo pla...
von Maltzahn, Geoffrey Ren, Yin Park, Ji-Ho Min, Dal-Hee Kotamraju, Venkata Ramana Jayakumar, Jayanthi Fogal, Valentina Sailor, Michael J Ruoslahti, Erkki Bhatia, Sangeeta N
...
Published in
Bioconjugate chemistry
The in vivo fate of nanomaterials strongly determines their biomedical efficacy. Accordingly, much effort has been invested into the development of library screening methods to select targeting ligands for a diversity of sites in vivo. Still, broad application of chemical and biological screens to the in vivo targeting of nanomaterials requires lig...
