Ruoslahti Research Laboratories at UC Santa Barbara and Sanford-Burnham
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Nanoparticles coated with the tumor-penetrating peptide iRGD reduce experimental breast cancer metastasis in the brain

Hamilton, Amanda M. Aidoudi-Ahmed, Sallouha Sharma, Shweta Kotamraju, Venkata R. Foster, Paula J. Sugahara, Kazuki N. Ruoslahti, Erkki Rutt, Brian K.

Published in Journal of Molecular Medicine

AbstractMetastasis is the main killer in cancer; consequently, there is great interest in novel approaches to prevent and treat metastatic disease. Brain metastases are particularly deadly, as the protection of the blood-brain barrier obstructs the passage of common anticancer drugs. This study used magnetic resonance imaging (MRI) to investigate t...

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